可实现对心房的指导性中风预防疗法
Jonathan P Piccini1, Haolin Xu1, Margueritte Cox1
1Duke Clinical Research Institute and Duke University Medical Center, Durham, NC (J.P.P., H.X., M.C., R.A.M.).
Circulation
|February 1, 2019
概括
在质量改善计划中,口服抗凝药 (OAC) 对心房患者的处方随着时间的推移显著改善. 可以实现高水平的推性中风预防,从79.9%增加到96.6%.
科学领域:
- 心脏病学
- 公共卫生
- 药理学
背景情况:
- 对心房患者的口服抗凝药 (OAC) 准则的遵守仍然是一个挑战.
- 之前改善OAC处方的努力取得了有限的成功.
研究的目的:
- 在CHA2DS2- VASc评分≥2的AF患者中评估OAC性能标准的遵守.
- 评估随着时间的推移OAC处方的趋势及其与住院结果的关联.
主要方法:
- 从美国心脏协会的Get With The Guidelines-AFIB注册表 (2013-2017) 中分析了33,235名AF患者.
- 在入院和出院时评估OAC处方率.
- 与OAC使用相关的住院结果的调整分析.
主要成果:
- 在入院时使用OAC与缺血性中风的几率降低有关 (OR,0. 38).
- 在研究期间,OAC在出院时的处方从79. 9%增加到96. 6% (P< 0. 0001).
- 在西班牙裔患者中使用OAC的比例较低 (90. 2%),而在年轻患者,男性和心力衰竭患者中使用OAC的比例较高.
结论:
- "与指导方针相处" - - AFIB质量改进计划导致OAC处方显著增加.
- 在AF患者中,可实现高水平的推性中风预防.
相关概念视频
Amyloid Fibrils
11.9K
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
11.9K
Amyloid Fibrils
6.4K
6.4K
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
446
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
446
Fibril-associated Collagen
3.4K
Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
3.4K
Guidelines for Writing Outcome
3.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
3.8K
Guidelines for Nursing Documentation I
1.8K
Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
Factual:
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
1.8K


