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Updated: Jan 30, 2026

Engineering Oncogenic Heterozygous Gain-of-Function Mutations in Human Hematopoietic Stem and Progenitor Cells
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Published on: March 10, 2023

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异卵性突变导致酵母癌症演变模型的遗传不稳定性

Miguel C Coelho1,2,3, Ricardo M Pinto4,5, Andrew W Murray6,7

  • 1FAS Center for Systems Biology, Harvard University, Cambridge, MA, USA. mcc150@gmail.com.

Nature
|February 1, 2019
PubMed
概括

单个基因突变会导致酵母的基因不稳定,加速进化并可能导致癌症. 这项研究确定了与不稳定性相关的新基因目标,对人类疾病研究有影响.

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