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Assessing Protein Interactions in Live-Cells with FRET-Sensitized Emission
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通过基于遗传密码扩展技术的FRET系统分析单个活细胞中的蛋白质相互作用

Seong-Hyun Park1, Wooseok Ko2, Hyun Soo Lee2

  • 1Center for Biofunctional Molecules, Department of Chemistry , Yonsei University , Seoul 03722 , Republic of Korea.

Journal of the American Chemical Society
|February 2, 2019
PubMed
概括

热冲击蛋白70 (Hsp70) 结合巴克斯抑制细胞灭绝. 新的FRET方法揭示了诱导细胞灭绝的物质如何破坏这种Hsp70-Bax相互作用,为细胞死亡调节提供了洞察力.

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