突发心脏病死亡的种族差异
Di Zhao1, Wendy S Post1,2, Elena Blasco-Colmenares1
1Departments of Epidemiology and Medicine, and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (D.Z., W.S.P., E.B.-C., E.D.M., E.G.).
Circulation
|February 5, 2019
概括
与白人相比,黑人面临心脏突发死亡 (SCD) 的风险明显更高,尤其是女性. 收入和教育等社会经济因素以及传统的风险因素解释了这种差异.
科学领域:
- 心脏病学
- 公共卫生
- 流行病学
背景情况:
- 黑人比白人有更高的非医院突然心脏死亡 (SCD) 发生率.
- 之前的研究还没有充分评估大型社区中累积性SCD风险的种族差异.
研究的目的:
- 为了比较黑人和白人的一生累积SCD风险.
- 确定导致SCD风险差异的风险因素.
主要方法:
- 一项由3832名黑人和11237名白人参与的社区动脉样硬化风险研究 (ARIC) 的队列研究.
- 使用竞争风险模型来计算累积发病率.
- 潜在的调解因素包括人口,社会经济地位,心血管风险因素和心电学参数.
主要成果:
- 在27.4年的时间里,SCD发生在215名黑人和332名白人的身上.
- 在85岁时,黑人男性的SCD累积发病率最高 (9.6%),白人女性的发病率最低 (2.3%).
- 已知因素解释了黑人与白人SCD风险的65.3%,收入,教育,高血压和糖尿病是主要因素.
结论:
- 与白人相比, 黑人, 尤其是女性, 患SCD的风险要高得多.
- 社会经济和传统心血管风险因素占SCD种族差异的很大一部分.
- 在SCD负担中观察到的种族和性别差异凸显了公共卫生和临床的重大挑战.
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