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Updated: Jan 29, 2026

RNA Pull-down Procedure to Identify RNA Targets of a Long Non-coding RNA
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一种非编码RNA的设计小分子抑制剂使HER2阴性癌症对Herceptin敏感

Matthew G Costales1, Dominic G Hoch1, Daniel Abegg1

  • 1Department of Chemistry , The Scripps Research Institute , 130 Scripps Way , Jupiter , Florida 33458 , United States.

Journal of the American Chemical Society
|February 7, 2019
PubMed
概括

一种新的小分子选择性地向miR- 515以增加基酶1 (SK1) 和基酸 (S1P) 的水平,使HER2-癌细胞对像Herceptin这样的抗HER2疗法敏感.

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