胸前动脉手术患者的性别相关差异
Jennifer Chung1, Louis-Mathieu Stevens2, Maral Ouzounian1
1University of Toronto, Canada (J.C., M.O., M.D.P.).
Circulation
|February 14, 2019
概括
女性在胸前动脉手术后的结果更糟. 女性的性别独立地预测了更高的死亡率和中风率,需要进一步研究性别特定的护理策略.
科学领域:
- 心血管外科
- 胸腔大动脉疾病
- 基于性别的医学
背景情况:
- 胸前动脉疾病的手术结果有所改善.
- 性对这些结果的影响仍然不太清楚.
研究的目的:
- 调查胸前动脉手术后与性别相关的结果差异.
主要方法:
- 在2002年至2017年间对1653名胸前动脉手术患者的分析.
- 性别之间的结局比较,包括住院死亡,中风和综合发病率终点.
- 多变量逻辑回归以确定结果的独立预测因素.
主要成果:
- 妇女年龄较大,并有更多的并发病,但对主动脉根进行的重建较少.
- 妇女的死亡率较高 (11% 与 7. 4% 相比) 和中风 (8. 8% 与 5. 5% 相比).
- 女性性别是死亡率,中风和复合发病率的独立预测因素.
结论:
- 女性在胸前动脉手术后面临更糟糕的结果,
- 需要进一步的研究来确定减少基于性别的结果差异的干预措施.
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