在人类B细胞受体中共享克隆类型的高频率

Cell-surface receptors, also known as transmembrane receptors, are cell surface, membrane-anchored (integral) proteins that bind to external ligand molecules. This type of receptor spans the plasma membrane and performs signal transduction, converting an extracellular signal into an intracellular signal. Ligands that interact with cell-surface receptors do not have to enter the cell that they affect. Cell-surface receptors are also called cell-specific proteins or markers because they are...

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.

Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.

Overview

A frequency is the number of times a value of the data occurs. The sum of all the frequency values represents the total number of students included in the sample. It is commonly used to group data of quantitative types. Frequency distributions can be displayed in a table, histogram, line graph, dot plot, or pie chart, just to name a few. A histogram is a graphical representation of tabulated frequencies, shown as adjacent rectangles, erected over discrete intervals (bins), with an area equal to...

Sometimes, data gathered from an experiment on a large sample or population are organized into concise tables. In such cases, the frequency of the quantitative data set is plotted in the form of a table. Or else, the data values are grouped into the quantity’s intervals, which form classes, and their respective frequencies are known. That is, the data values are distributed over different categories or classes. This is known as frequency distribution.
When such a data set is encountered,...