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Updated: Jan 29, 2026

Detection of Protein Ubiquitination
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Published on: August 19, 2009

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通过Dot1L进行的H2B化和H3甲基化交叉交谈的机制

Evan J Worden1, Niklas A Hoffmann1, Chad W Hicks1

  • 1Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|February 16, 2019
PubMed
概括

基因组H2B泛化 (H2B-Ub) 刺激了基因组H3K79的Dot1L甲基化. 这种交叉交谈涉及H4尾部,并诱导基因组H3的结构变化,使K79能够获得活跃的基因转录.

关键词:
时间点1L染色体化电磁场基因子甲基化核子体结构生物学无处不在的

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