高强度间歇训练对斯堪的纳维亚心脏移植患者的影响
Kari Nytrøen1,2,3,4, Katrine Rolid1,2,3,5,4, Arne Kristian Andreassen1,2
1Departments of Cardiology (K.N., K.R., A.K.A., M.Y., E.G., E.B., A.R.A., I.G., L.G.), Oslo University Hospital Rikshospitalet, Norway.
Circulation
|February 19, 2019
概括
高强度间歇训练 (HIT) 提高了心脏移植患者的运动能力. 与中等强度训练相比, 这种安全有效的方法在心脏移植后很早开始使用,
科学领域:
- 心脏病学
- 运动生理学
- 移植医学
背景情况:
- 在心脏移植 (HTx) 后的最佳运动方案上存在有限的共识.
- 之前的研究表明高强度间歇训练 (HIT) 在HTx后的维护阶段是安全有效的.
- 在早期的新型HTx状态下,HIT的影响仍未得到充分研究.
研究的目的:
- 研究早期高强度间歇训练 (HIT) 的安全性和有效性.
- 比较HIT与中等强度持续训练 (MICT) 对运动能力和生活质量的影响.
- 测试HIT可以导致HTx后运动能力和生活质量的临床上有意义的改善的假设.
主要方法:
- 一个多中心,前性,随机对照试验,涉及81名新生HTx患者 (移植后平均11周).
- 患者被随机分配到9个月的HIT (4x4分钟间隔在85% - 95%的峰值努力) 或MICT (60% - 80%的峰值努力).
- 主要结果:高氧消耗量变化;次要结果:肌肉强度,身体组成,生活质量,心脏功能和血液动力学.
主要成果:
- 96% 的患者完成了该研究,没有严重的运动相关不良事件.
- 与MICT相比,HIT组的Vo2峰值 (1.8mL·kg-1·min-1差异,约0. 5METs),无氧值,最大排气流量和伸缩肌肉容量有明显的改善.
- 在HIT和MICT组中,与健康相关的生活质量结果相似.
结论:
- 高强度间歇训练 (HIT) 是对心脏移植患者的一种安全有效的运动方式.
- 早期实施HIT导致运动能力的临床显著改善,包括VO2峰值,无氧值和肌肉力量.
- 在心脏移植后提高运动能力方面,HIT表现出比中等强度持续训练更高的效率.
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