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Updated: Feb 13, 2026

Author Spotlight: Refining Xenopus laevis Marking Techniques for Biomedical Studies
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Published on: June 28, 2024

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线粒体突变和单细胞基因组学使人类的血统追踪成为可能

Leif S Ludwig1, Caleb A Lareau2, Jacob C Ulirsch3

  • 1Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

Cell
|March 5, 2019
PubMed
概括

科学家现在可以使用线粒体DNA (mtDNA) 中发现的自然遗传条形码来追踪人类细胞系. 这种方法提供了1000倍的尺度,并为研究健康和疾病提供了细胞状态信息.

关键词:
慢性骨髓性白血病大肠癌血液形成血统追踪线粒体DNA它们的 mtDNA测序方式单细胞基因组学身体突变

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