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Updated: Jan 28, 2026

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq
06:22

Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq

Published on: August 25, 2020

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单细胞RNA-Seq揭示了与疾病进展和免疫相关的AML等级

Peter van Galen1, Volker Hovestadt1, Marc H Wadsworth Ii2

  • 1Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Ludwig Center at Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Cell
|March 5, 2019
PubMed
概括

这项研究揭示了急性髓性白血病 (AML) 的不同细胞类型,将基因突变与特定细胞状态联系起来. 这些发现为AML的进展和潜在的精准医学目标提供了洞察力.

关键词:
急性骨髓性白血病癌症遗传学基因定型豁免权白血病干细胞单细胞RNA测序

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