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通过Akt介导的NAD激酶酸化直接刺激NADP+合成

Gerta Hoxhaj1, Issam Ben-Sahra2, Sophie E Lockwood1

  • 1Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Science (New York, N.Y.)
|March 9, 2019
PubMed
概括

增长因子信号通过Akt酸化激活NAD激酶 (NADK),促进代谢必需的NADP+生产. 这种调节增强了减少细胞过程的NADPH可用性.

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