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Updated: Jan 27, 2026

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在最多三个不同的位置进行精确的蛋白质标记的相互直角无意义抑制系统和结合化学

James S Italia1, Partha Sarathi Addy1, Sarah B Erickson1

  • 1Department of Chemistry , Boston College , 2609 Beacon Street, 246B Merkert Chemistry Center , Chestnut Hill , Massachusetts 02467 , United States.

Journal of the American Chemical Society
|March 27, 2019
PubMed
概括

科学家们开发了一种新方法,使用直角遗传密码将多达三种不同的非正规氨基酸 (ncAAs) 插入蛋白质中. 这一突破为高级生物应用提供了精确的多部位蛋白质标签.

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Conjugated Proteins02:50

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Organic compounds with conjugated double bonds show strong absorption features in the UV–visible region of the electromagnetic spectrum attributed to π → π* electronic excitations. Generally, a UV–vis absorption spectrum is recorded as a plot of absorbance vs wavelength. The wavelength of maximum absorbance, which manifests as a peak in the absorption spectrum, is denoted as λmax.
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