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Updated: Jan 26, 2026

T Cells Capture Bacteria by Transinfection from Dendritic Cells
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释放2型树突细胞驱动保护性抗瘤CD4+T细胞免疫力

Mikhail Binnewies1, Adriana M Mujal1, Joshua L Pollack2

  • 1Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.

Cell
|April 9, 2019
PubMed
概括

瘤透性骨髓细胞,特别是传统的2型树突细胞 (cDC2),抑制抗瘤CD4+T细胞的反应. 减少调节性T细胞 (Tregs) 逆转了这种情况,增强了CD4+T细胞的活性,并改善了抗瘤保护.

关键词:
CD4 ((+) T细胞T细胞启动检查点封锁树突细胞免疫疗法监管T细胞瘤免疫学瘤微环境

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