迪亚利-λ3-chloranes:多功能合成和独特的反应性作为酸盐等价物
Misuzu Nakajima1, Kazunori Miyamoto1, Keiichi Hirano1
1Graduate School of Pharmaceutical Sciences , The University of Tokyo , 7-3-1 Hongo , Bunkyo-ku, Tokyo 113-0033 , Japan.
Journal of the American Chemical Society
|April 11, 2019
概括
一种新的合成方法可以从和盐中产生二/λ3. 这些化合物对电友和素交换反应具有独特的反应性.
科学领域:
- 有机化学
- 合成化学
- 有机金属化学
背景情况:
- 酸盐和酸是重要的合成中间体.
- 现有的合成方法可能范围有限或需要严格的条件.
研究的目的:
- 开发一种多功能且高产的二甲/λ3合成.
- 探索合成的二甲/λ3-的反应性.
主要方法:
- 各种素 (ArCl,ArBr,ArI) 与甲 (pentafluorophenyl) 酸盐的反应
- 使用了轻度反应条件.
主要成果:
- 成功合成了广泛的二甲/λ3.
- 证明了独特的反应性,包括弱核友的分子间电友性结合.
- 展示了与的交换反应.
结论:
- 开发的方法提供了一种多功能和高产的途径,用于diarylchloroniums/λ3-chloran.
- 合成的化合物为合成应用提供了新的反应性.
相关概念视频
Other Unique Bacteria
429
Magnetic bacteria exhibit a directed movement called magnetotaxis, driven by structures called magnetosomes. These magnetosomes consist of chains of magnetic particles made of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and are organized in a linear conformation by a protein scaffold within invaginations of the cell membrane. The bacteria align along the north–south magnetic field lines, much like a compass needle. They are typically microaerophilic or anaerobic...
429
Second Uniqueness Theorem
2.6K
Consider a region consisting of several individual conductors with a definite charge density in the region between these conductors. The second uniqueness theorem states that if the total charge on each conductor and the charge density in the in-between region are known, then the electric field can be uniquely determined.
In contrast, consider that the electric field is non-unique and apply Gauss's law in divergence form in the region between the conductors and the integral form to the surface...
In contrast, consider that the electric field is non-unique and apply Gauss's law in divergence form in the region between the conductors and the integral form to the surface...
2.6K
Pharmaceutical Equivalents
193
As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
193
Equivalent Capacitance
2.1K
Multiple capacitors can be connected in a circuit in series or parallel configuration. When the capacitor combination is connected to a battery, the potential drop across each capacitor and the magnitude of charge stored in the individual capacitor depends on the type of the connection. The capacitor combination is replaced by a single equivalent capacitor that stores the same amount of charge as the combination for a given potential difference.
The following strategies are adopted to calculate...
The following strategies are adopted to calculate...
2.1K
Equivalent Capacitance
688
From the study of resistive circuits, it is understood that employing a series-parallel combination serves as an effective strategy for simplifying circuits. Capacitors can be arranged within a circuit in one of two ways: a series configuration or a parallel configuration. The way these capacitors are connected to a battery will influence both the potential drop across each individual capacitor and the size of the charge that each capacitor can store. This is determined by the specific type of...
688
Nomenclature of Aryl and Heterocyclic Amines
3.1K
The simplest aromatic amine is phenylamine, which contains an –NH2 functionality directly attached to an aromatic ring. The name aniline is designated for this skeleton. As shown in Figure 1, the common names of the functionalized anilines involve prefixes ortho-, meta-, and para- to indicate the substitution position. Different functionalized aniline derivatives also have notable trivial names.
3.1K


