解码增加自组装三胺体尺寸对体放大的影响
Elisa E Greciano1, Joaquín Calbo2, Julia Buendía1
1Departamento de Química Orgánica, Facultad de Ciencias Químicas , Universidad Complutense de Madrid , 28040 Madrid , Spain.
Journal of the American Chemical Society
|April 16, 2019
概括
这项研究研究了超分子聚合物的奇拉放大. 减少性侧链在基乙烯) 三胺降低了螺旋反转处罚,增加了不匹配处罚,影响了螺旋结果.
科学领域:
- 超分子化学
- 聚合物科学
- 奇拉性研究
背景情况:
- 超分子聚合物自组成有序的结构.
- 状放大对于产生特定的螺旋结果至关重要.
- 奥利戈乙烯三胺 (OPE-TA) 是研究超分子聚合的模型系统.
研究的目的:
- 研究单体结构对超分子聚合物的影响.
- 在OPE-TA中确定控制力放大的热力学参数.
- 为了比较OPE-TAs与二胺 (BTAs) 的奇拉放大.
主要方法:
- 使用海员和士兵 (SaS) 和多数规则 (MR) 实验的实验调查.
- 分析单体相互作用和螺旋结构的理论计算.
- 确定热力学参数,如螺旋反转处罚 (HRP) 和不匹配处罚 (MMP).
主要成果:
- 随着奇拉侧链减少,HRP降低,而MMP增加.
- 与BTA相比,OPE-TA显示了不同的奇拉放大趋势.
- 理论计算将较小的旋转角度与较高的MMP和较低的HRP相关联.
结论:
- 单体结构,特别是奇拉侧链的数量,显著影响了高分子聚合物螺旋性.
- 自组装单元的尺寸是控制合转移和放大的一个关键因素.
- 了解这些参数是设计功能性性超分子材料的关键.
相关概念视频
Chirality
29.3K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
29.3K
Chirality in Nature
17.0K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
17.0K
Timing and Consequences on Behavior
372
In operant conditioning, the timing of reinforcement is crucial. For animals like rats and cats, immediate reinforcement (within a few seconds) is much more effective than delayed reinforcement. For example, a food reward for a rat needs to follow within 30 seconds of pressing a bar to be effective.
Humans, however, can respond to delayed reinforcers. We often make decisions between immediate small rewards and delayed larger rewards. This ability to delay gratification is a significant...
Humans, however, can respond to delayed reinforcers. We often make decisions between immediate small rewards and delayed larger rewards. This ability to delay gratification is a significant...
372
Molecules with Multiple Chiral Centers
14.9K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
14.9K
Chirality at Nitrogen, Phosphorus, and Sulfur
6.9K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
6.9K
Cell Size
126.7K
Cell sizes vary widely among and within organisms. Bacterial cells range between 1-10 micrometers (μm)and are considerably smaller than most eukaryotic cells. The smallest bacteria are 0.1 μm in diameter—about a thousand times smaller than eukaryotic cells, which typically range from 10-100 μm.
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
Surface Area
Cells can take in nutrients and water via diffusion through the plasma membrane itself or through specific channels in the membrane. The area of the membrane surrounding...
126.7K


