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SiRA:一种用于活细胞超分辨率RNA成像的罗达胺结合性吸收剂

Regina Wirth1, Peng Gao2,3, G Ulrich Nienhaus2,3,4,5

  • 1Institute of Pharmacy and Molecular Biotechnology (IPMB) , Heidelberg University , 69120 Heidelberg , Germany.

Journal of the American Chemical Society
|April 16, 2019
PubMed
概括

研究人员开发了一种新型的RNA吸收酶 (SiRA),可以结合罗达胺 (SiR) 染料,从而使活细胞RNA成像具有明亮,光稳定的远红色光辐射. 该系统使用超分辨率显微镜对细菌和活细胞中的RNA进行了增强的可视化.

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