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Updated: Jan 25, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
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小分子抑制剂的BfrB-Bfd 相互作用 降低Pseudomonas aeruginosa 适应性和潜在的基诺活性

Achala N D Punchi Hewage1, Huili Yao2, Baskar Nammalwar3

  • 1Department of Chemistry , University of Kansas , 2030 Becker Drive , Lawrence , Kansas 66047 , United States.

Journal of the American Chemical Society
|May 1, 2019
PubMed
概括

研究人员开发了小分子抑制剂,针对细菌储铁蛋白细菌铁蛋白 (BfrB) 和其与铁素 (Bfd) 的相互作用. 这些抑制剂破坏P. aeruginosa的铁稳定,在组合疗法中显示出潜力.

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