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在癌症免疫治疗期间,CD8+T细胞调节瘤铁

Weimin Wang1,2, Michael Green2,3, Jae Eun Choi2,4,5

  • 1Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI, USA.

Nature
|May 3, 2019
PubMed
概括

癌症免疫疗法增强了CD8+T细胞功能,通过铁死促进了瘤细胞的死亡. 干扰素 (IFNγ) 降低了囊的摄取,增加了脂质过氧化,并有助于抗瘤功效. 结合疗法是有前途的

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