用广泛的古代基因组时间序列追踪五千年马的管理
Antoine Fages1, Kristian Hanghøj1, Naveed Khan2
1Laboratoire d'Anthropobiologie Moléculaire et d'Imagerie de Synthèse, CNRS UMR 5288, Université de Toulouse, Université Paul Sabatier, 31000 Toulouse, France; Lundbeck Foundation GeoGenetics Center, University of Copenhagen, 1350K Copenhagen, Denmark.
Cell
|May 7, 2019
概括
古老的马DNA揭示了灭绝的血统,并强调了现代的繁殖
科学领域:
- 古代基因组学
- 马类进化生物学
- 化研究
背景情况:
- 马的化对人类历史产生了深远的影响, 影响了战争,旅游和语言的传播.
- 了解马的遗传历史对于解读它们在过去文明中的作用至关重要.
研究的目的:
- 重建马匹养和管理的遗传时间表.
- 发现古代马族对现代人类的遗传贡献.
- 评估历史事件和现代育种对马的遗传多样性的影响.
主要方法:
- 对149只古老的马进行基因组规模的DNA分析,其中包括87个新测序的基因组.
- 古代和现代马种群的比较基因组分析.
- 随着时间的推移对遗传多样性和血统贡献的分析.
主要成果:
- 从早期化 (伊比利亚,西伯利亚) 的两种灭绝的马系对现代马的影响很小.
- 在伊斯兰教征服后,与波斯相关的马系变得越来越突出.
- 与精英赛车相关的等位基因,如MSTN变种,在过去的千年中获得了普及.
- 现代的马种养殖方式对遗传多样性产生了比人类几千年的管理更大的影响.
结论:
- 古代的马种群是多样化的,在化初期出现了不同的血统.
- 人类的历史事件和选择性繁殖方式塑造了马的遗传.
- 现代育种已经大大减少了马的遗传多样性,
相关概念视频
Time-Series Graph
5.0K
A time-series graph is a line graph with repeated measurements taken at successive intervals of time. It is also called a time series chart. To construct a time-series graph, one must look at both pieces of a paired data set. The horizontal axis is used to plot the time increments, and the vertical axis is used to plot the values of the variable that one is measuring. By using the axes in this way, each point on the graph will correspond to time and a measured quantity. The points on the graph...
5.0K
Discrete-Time Fourier Series
671
The Discrete-Time Fourier Series (DTFS) is a fundamental concept in signal processing, serving as the discrete-time counterpart to the continuous-time Fourier series. It allows for the representation and analysis of discrete-time periodic signals in terms of their frequency components. Unlike its continuous counterpart, which utilizes integrals, the calculation of DTFS expansion coefficients involves summations due to the discrete nature of the signal.
For a discrete-time periodic signal x[n]...
For a discrete-time periodic signal x[n]...
671
Genomics
39.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.9K
Resistors In Series
6.1K
A resistor is an ohmic device that limits the flow of charge in a circuit. Most circuits have more than one resistor. If several resistors are connected together and connected to a battery, the current supplied by the battery depends on the equivalent resistance of the circuit. The equivalent resistance of a combination of resistors depends on both their individual values and how they are connected. The simplest combination of resistors is the series combination.
In a series circuit, the...
In a series circuit, the...
6.1K
Series Resonance
786
The RLC circuit impedance is defined as the ratio of the supply voltage to the circuit current. Resonance in such a circuit occurs when the imaginary part of this impedance equals zero. This specific condition means that the inductive reactance is exactly equal to the capacitive reactance. The frequency at which this happens is known as the resonant frequency. Mathematically, the resonant frequency is inversely proportional to the square root of the product of the inductance (L) and capacitance...
786
Trigonometric Fourier series
774
Fourier series is a foundational mathematical technique that decomposes periodic functions into an infinite series of sinusoidal harmonics. This method enables the representation of complex periodic signals as sums of simple sine and cosine functions, facilitating their analysis and interpretation in various fields, including signal processing, acoustics, and electrical engineering.
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
The trigonometric Fourier series specifically expresses a periodic function with a defined period T using sine...
774


