孕期体重增加与母亲和婴儿不良结果的关联
, Ellis Voerman1,2, Susana Santos1,2
1Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
JAMA
|May 8, 2019
概括
最佳的妊娠体重增加取决于妊娠前的体重指数 (BMI). 这项研究确定了不同BMI类别的特定体重增加范围,以减少对母亲和婴儿的不良结果.
科学领域:
- 母婴健康
- 产科和妇科
- 公共卫生
背景情况:
- 不足或过度的妊娠体重增加 (GWG) 都与母亲和婴儿的不良结果有关.
- 在所有怀孕前的体重指数 (BMI) 类别中,GWG的最佳范围尚未确定.
研究的目的:
- 分析GWG范围与母亲/婴儿不良结果之间的关联.
- 为了确定各种孕前BMI类别的最佳GWG范围.
主要方法:
- 来自25个队列研究中的196,670名女性的个人参与者层面的元分析.
- 最佳GWG范围被定义为与最低不良结果风险相关的范围.
- 使用3,505名其他参与者的数据进行验证.
主要成果:
- 根据GWG和妊娠前的BMI,不良结果的风险有显著差异.
- 确定了每个BMI类别的最佳GWG范围,例如正常体重为10. 0- 16. 0公斤,肥胖1级为2. 0- 6. 0公斤.
- 这些范围对结果的预测价值有限.
结论:
- 应根据个体的妊娠前BMI量身定制GWG建议.
- 虽然确定了最佳范围,但它们对特定不良结果的预测能力是中等的.
- 调查结果可以为产前咨询提供有关GWG的信息.
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