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LMBR1L通过Wnt/β-catenin信号调节淋巴发育

Jin Huk Choi1, Xue Zhong1, William McAlpine1

  • 1Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|May 11, 2019
PubMed
概括

肢体区域1-like基因 (Lmbr1l) 的突变通过破坏Wnt信号调节来损害免疫细胞的发育. Lmbr1l 缺乏导致T细胞缺陷和亡,突出显示其在淋巴细胞形成中的关键作用.

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