A RNPPan2-Pan3

Ingmar B Schäfer1, Masami Yamashita1, Jan Michael Schuller1

  • 1Department of Structural Cell Biology, MPI of Biochemistry, Munich, Germany.

Cell
|May 21, 2019
PubMed
概括

多A结合蛋白 (PABPC1/Pab1) 通过与Pan2-Pan3死亡酶复合体相互作用来调节mRNA的稳定性. 结构分析揭示了多甲尾的Pab1寡合体如何决定mRNA死亡化率.

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