可编程高吞吐量平台,用于快速和可扩展的聚和聚碳酸盐库
Binhong Lin1, James L Hedrick2, Nathaniel H Park2
1Department of Chemistry , Stanford University , Stanford , California 94305 , United States.
Journal of the American Chemical Society
|May 24, 2019
概括
研究人员开发了一种快速可扩展的方法, 使用连续流动反应器和有机催化剂制造多种聚和聚碳酸材料. 这种方法精确地控制了聚合物结构的定制性质.
科学领域:
- 聚合物化学
- 材料科学
- 有机合成
背景情况:
- 宏分子材料的特性取决于对组成,结构,分子量和分布的精确控制.
- 现有的合成方法往往缺乏探索完整结构属性景观所需的可重现性,可扩展性和可编程性.
研究的目的:
- 开发一种快速,可控和可扩展的方法来合成聚和聚碳酸同聚合物和块共聚合物.
- 用有机催化剂和连续流反应器来精确控制大分子合成.
主要方法:
- 在编程连续流反应器中使用可调和和高活性有机催化剂.
- 实现了高度控制的聚合,停留时间短 (低至6毫秒),转换频率高 (TOF=24,000,000小时-1).
- 实施了进流催化剂开关策略,以实现高效的块共聚合物合成.
主要成果:
- 成功生成了高效率和控制的聚和聚碳酸同聚合物和块共聚合物的库.
- 已经证明可以以每分钟几十克的速度生产聚合物.
- 在短短9分钟内迅速合成了100个不同的区块共聚物,
结论:
- 有机催化剂和连续流反应器的组合为可编程大分子合成提供了强大的平台.
- 这种方法可以快速探索聚和聚碳酸的结构性质关系.
- 开发的技术为创建先进的聚合物材料提供了强大的可扩展方法.
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