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Updated: May 7, 2026

Detection and Isolation of Viable Mouse IL-17-Secreting T Cells
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Published on: December 18, 2008

在小鼠细胞分解性淋巴细胞中识别,分离和描述一种新型细胞毒素

C C Liu1, M Steffen, F King

  • 1Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York, New York 10021.

Cell
|November 6, 1987
PubMed
概括

细胞毒性T淋巴细胞具有一种新型的细胞分解因子,与穿孔素,瘤缩因子 (TNF) 和淋巴毒素 (LT) 不同. 这种新发现的CTL细胞毒素诱导了目标细胞中的DNA分裂,这表明了多个淋巴细胞杀死机制.

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...