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Updated: Jan 23, 2026

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一个小分子向突变转化合成改善化疗

Jessica L Wojtaszek1, Nimrat Chatterjee2, Javaria Najeeb1

  • 1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

Cell
|June 11, 2019
PubMed
概括

研究人员开发了一种新的小分子抑制剂JH-RE-06,以向突变转化合成 (TLS). 这一突破通过阻断药物耐药性和减少治疗诱导的突变来提高化疗效果.

关键词:
美国实际价值1REV7 时间化学阻力化学疗法西斯普拉丁转化合成

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