的公共卫生控制:研究和行动的优先事项
Daniel Engelman1, Paul T Cantey2, Michael Marks3
1Tropical Diseases Group, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Department of General Medicine, Royal Children's Hospital, Melbourne, VIC, Australia.
Lancet (London, England)
|June 11, 2019
概括
是一种被忽视的热带疾病, 需要进行研究以指导大规模药物管理,以有效根除并减少其严重的健康影响.
科学领域:
- 流行病学
- 传染性疾病
- 公共卫生
背景情况:
- 是一种被忽视的热带疾病,
- 它会导致严重的疾病,包括严重的细菌和免疫媒介疾病.
- 最近的进展表明通过大规模药物管理来控制人口是可行的.
研究的目的:
- 为制定全球控制计划概述关键的运营研究问题.
- 解决对标准化诊断和绘制方法的需求.
- 引导大规模药物管理战略的优化.
主要方法:
- 根据当前的科学认识和世卫组织的认可,该研究确定了关键研究领域.
- 它强调需要标准化的诊断工具和疾病负担映射.
- 它要求对幼儿治疗的安全性调查和最佳群体治疗参数.
主要成果:
- 标准化诊断和测绘方法对于了解病负担至关重要.
- 需要进一步研究ivermectin和moxidectin在幼儿中的安全性.
- 需要研究最佳的群体治疗策略,包括干预值,目标,剂量和频率.
结论:
- 解决关键的运营研究问题对于全球控制计划至关重要.
- 标准化方法和安全数据是有效的人口层面干预的先决条件.
- 发展监督,监测和评估框架对于长期成功至关重要.
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