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Updated: Jan 23, 2026

Selective Capture of 5-hydroxymethylcytosine from Genomic DNA
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Selective Capture of 5-hydroxymethylcytosine from Genomic DNA

Published on: October 5, 2012

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可编程的蛋白质-DNA交叉链接用于直接捕获和定量5-甲基细胞素

Mario Gieß1, Álvaro Muñoz-López1, Benjamin Buchmuller1

  • 1Faculty of Chemistry and Chemical Biology , TU Dortmund University , Otto-Hahn-Str. 6 , 44227 Dortmund , Germany.

Journal of the American Chemical Society
|June 11, 2019
PubMed
概括

研究人员开发了一种基于TALE的新方法来检测DNA中的表观遗传标记5-formylcytosine (5fC). 这种技术在表观遗传学研究中使用共价交叉链接进行敏感和特定的5fC量化.

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