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对抗合成阿片类药物中毒的单克隆抗体

Lauren C Smith1, Paul T Bremer1,2, Candy S Hwang1,3

  • 1Departments of Chemistry, Immunology and Microbial Science, Skaggs Institute for Chemical Biology , The Scripps Research Institute , 10550 N Torrey Pines Road , La Jolla , California 92037 , United States.

Journal of the American Chemical Society
|June 13, 2019
PubMed
概括

研究人员开发了单克隆抗体 (mAbs) 来治疗合成阿片类药物的过量服用. 这些抗体有效地逆转了小鼠的芬太尼和卡芬太尼效应,为阿片类药物成和过量服用提供了潜在的新疗法.

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