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在晚期前列腺癌中激活FOXA1变化的不同结构类别

Abhijit Parolia1,2,3, Marcin Cieslik1,2,4, Shih-Chun Chu1,2

  • 1Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA.

Nature
|June 28, 2019
PubMed
概括

前列腺癌中的叉头盒A1 (FOXA1) 变化分为三类,这些变化导致瘤发生和转移. 了解这些FOXA1变化为激素驱动的癌症提供了新的治疗策略.

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