相关实验视频
Updated: Aug 2, 2026
16:11
Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
概括
这项研究表明,在心脏手术后,即使没有常规抗凝药,也可以在患有急性左心室衰竭的患者中拯救生命. 机械循环支持有效地降低了压力,并保持了心脏输出.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 胸部外科手术 胸部外科手术
背景情况:
- 吸收性心脏性休克是心脏手术后危及生命的并发症.
- 机械循环支持为严重的左心室衰竭提供了潜在的解决方案.
- 在这种情况下,先前对异种移植式的研究是有限的.
研究的目的:
- 评估一台用于暂时循环支持的副体气动异体移植气的有效性和安全性.
- 评估机械循环支持对血液动力学参数和患者结果的影响.
- 为了调查出血和栓塞等并发症的发生.
主要方法:
- 在心脏手术后,八名患有难以治疗的心脏性休克的患者使用体式,气动式,异种植入气获得了循环支持.
- 连接在左心室顶部和上升性大动脉之间.
- 血液动力学参数,血血红蛋白,红细胞脆弱性,血小板计数和全身栓塞都被监测.
主要成果:
- 辅助有效降低左心房和心室压力,同时保持心脏输出 (1.8-2.6 L/min/m2).
- 血血红蛋白升高和红细胞机械脆弱性正常化,功能不受损害.
- 所有患者都出现了血栓塞缩症,五例有严重出血;然而,尽管使用抗凝剂有限,但没有检测到全身栓塞.
结论:
- 在心脏手术后的急性左心室衰竭中,副体气动异体移植支持可以挽救生命.
- 该设备在血液动力学稳定方面表现出有效性.
- 仔细监测出血是至关重要的,但如果没有常规抗凝治疗,全身栓塞的风险似乎很低.
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