BRCA

Philip Jonsson1,2,3, Chaitanya Bandlamudi1, Michael L Cheng4,5

  • 1Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|July 12, 2019
PubMed
概括

BRCA1和BRCA2基因的生殖基因和体质突变与遗传性癌症有关. 然而,它们的影响因瘤类型而异,有些癌症受益于向治疗,而另一些癌症则显示BRCA突变在生物学上是中立的.

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