通过电化学氧化合硫化和化的合成
Gabriele Laudadio1, Aloisio de A Bartolomeu1,2, Lucas M H M Verwijlen1
1Micro Flow Chemistry and Synthetic Methodology, Department of Chemical Engineering and Chemistry , Eindhoven University of Technology , Het Kranenveld, Bldg 14 - Helix , 5600 MB Eindhoven , The Netherlands.
Journal of the American Chemical Society
|July 16, 2019
概括
研究人员开发了一种绿色电化学方法,从硫醇或二硫化物中合成硫. 这种高效的方法使用化 (KF),避免额外的氧化剂或催化剂,为点击化学应用提供广泛的基质范围.
科学领域:
- 有机化学
- 电化学
- 合成方法
背景情况:
- 硫化物是有机合成中的关键功能组.
- 硫化物交换 (SuFEx) 突出了硫化物的重要性.
- 有效和温和的合成化路径是非常可取的.
研究的目的:
- 开发一种新的,温和的,对环境无害的硫化物电化学合成方法.
- 使用易于获得的材料,如硫化物和硫化物.
- 使用一种廉价且安全的化物来源,即化物 (KF).
主要方法:
- 在KF的存在下电化学氧化硫醇或二硫化物.
- 使用温和的反应条件.
- 避免需要外部氧化剂或催化剂.
主要成果:
- 在电化学条件下成功合成硫.
- 已证明广泛的基质范围,包括基,基,基和异基二醇/二硫化物.
- 这种方法有效,温和,环保.
结论:
- 已经建立了一种新的绿色电化学方法来合成硫.
- 这种方法为获取有价值的硫化基提供了可持续的替代方案.
- 这种方法适用于各种基板,促进了点击化学中的多种应用.
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