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美国预防服务特别工作组:怀孕妇女的乙型肝炎病毒感染查
, Douglas K Owens1,2, Karina W Davidson3
1Veterans Affairs Palo Alto Health Care System, Palo Alto, California.
JAMA
|July 24, 2019
概括
检查孕妇是否感染乙型肝炎病毒 (HBV) 对于预防婴儿传播至关重要. 证据证实查提供了实质性的益处,从而再次证实了产前HBV检测的建议.
科学领域:
- 肝病学和传染病
- 公共卫生和预防医学
- 产科和妇科
背景情况:
- 孕产妇感染乙型肝炎病毒 (HBV) 存在传染给婴儿的危险.
- 尽管有婴儿疫苗接种指导方针,但母婴HBV感染率有所上升,增加了儿童慢性感染的可能性.
- 慢性HBV感染导致严重的长期健康后果,包括肝硬化和癌症.
研究的目的:
- 更新2009年美国预防服务工作组 (USPSTF) 对孕妇HBV感染查的建议.
- 评估查和病例管理对预防周围HBV传播的有效性和危害的新证据.
主要方法:
- 一个确认证据更新由USPSTF委托.
- 这项审查重点关注怀孕妇女对HBV感染的查的有效性和潜在危害.
- 此外,还评估了预防围产期传播病例管理的有效性和危害.
主要成果:
- 对乙型肝炎表面抗原的血清检测可以准确地识别HBV感染.
- 包括病例管理计划在内的干预措施有效防止围产期HBV传播.
- 病例管理表明,随着时间的推移,围产期传播率有所下降,为健康带来了显著的益处.
结论:
- 美国公共卫生检查委员会重申其结论,对孕妇进行HBV感染查有很大的好处.
- 有令人信服的证据支持在孕妇中查HBV感染的有效性.
- 美国妇产科医院推在孕妇的第一次产前检查中对HBV感染进行查.
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