具有聚合诱导发射和循环偏光的螺旋硫-γ-AA
Yan Shi, Guangqiang Yin, Zhiping Yan1
1State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering , Nanjing University , Nanjing 210023 , China.
Journal of the American Chemical Society
|July 24, 2019
概括
研究人员开发了新的四乙烯 (TPE) 修饰的硫-γ-AA. 这些中等分子重量的支架表现出聚合诱导的辐射增强和循环极化发光,显示出材料和生物医学应用的潜力.
科学领域:
- 超分子化学
- 有机化学
- 材料科学
背景情况:
- 聚合诱导排放 (AIE) 对光原体至关重要,但具有精确AIE单位的中等分子重量支架很少.
- 四乙烯 (TPE) 是一个众所周知的AIE发光剂.
研究的目的:
- 合成和研究具有受控制的AIE特性的TPE修饰的硫-γ-AA.
- 探索它们在循环偏光 (CPL) 和生物医学成像中的潜力.
主要方法:
- 三种TPE修饰的硫-γ-AA的合成.
- 对TPE-α/sulfono-γ-AA的晶体结构分析
- 光光谱学用于研究AIE和聚合诱导的辐射增强 (AIEE).
- 循环偏光 (CPL) 的测量.
主要成果:
- 刚性螺旋支架限制了TPE的旋转,增强了溶液中的光.
- 由于AIE和受限旋转的结合,2和3显示出AIEE.
- 螺旋结构促进了预定向组装,从而产生具有高不对称系数 (g_lum) 的有效CPL信号.
- 两性质使细菌能够透细胞膜并产生强烈的光.
结论:
- 修改为TPE的硫-γ-AA是一种新型的中等分子量AIE发光剂.
- 它们的螺旋结构允许调节AIE,AIEE和CPL属性.
- 这些化合物由于它们的膜透性和无标签性而具有抗菌应用和光标签的前景.
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