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Updated: Jan 21, 2026

Studying the Role of Alveolar Macrophages in Breast Cancer Metastasis
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通过巨细胞传递CD24信号的Siglec-10是癌症免疫治疗的目标

Amira A Barkal1,2,3,4, Rachel E Brewer1,2,3, Maxim Markovic1,2,3

  • 1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Nature
|August 2, 2019
PubMed
概括

癌细胞通过CD47和PD-L1等"不要吃我"信号来逃避免疫检测. 研究人员发现CD24作为主导性免疫检查点,阻断巨细胞清除,并为卵巢和乳腺癌提供新的免疫治疗点.

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