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Updated: Jan 21, 2026

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动态质子会极大地影响类似药物分子的膜透性

Zhi Yue1, Chenghan Li1, Gregory A Voth1

  • 1Department of Chemistry, James Frank Institute, and Institute for Biophysical Dynamics , The University of Chicago , Chicago , Illinois 60637 , United States.

Journal of the American Chemical Society
|August 7, 2019
PubMed
概括

通过动态中和更好地了解带电的药物穿透膜. 这项研究揭示了propranolol如何在脂质接口中中和,改善了药物吸收和发育的模型.

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