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Updated: Jan 21, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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Published on: June 15, 2011

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遗传和De Novo遗传风险对自闭症的影响

Elizabeth K Ruzzo1, Laura Pérez-Cano2, Jae-Yoon Jung3

  • 1Department of Psychiatry and Biobehavioral Sciences, Semel Institue, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.

Cell
|August 10, 2019
PubMed
概括

研究人员确定了69个与自闭症谱系障碍 (ASD) 风险相关的基因,其中包括16个新基因,主要是通过多重家族中的罕见遗传变异. 这项研究促进了对自闭症遗传学的理解, 并确定了新的生物学途径.

关键词:
自闭症自闭症在新遗传学遗传的机器学习多重家庭

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