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Updated: Jan 20, 2026

Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope
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Force Spectroscopy of Single Protein Molecules Using an Atomic Force Microscope

Published on: February 28, 2019

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通过分子动力学模拟和单分子力谱学揭示的蛋白质复合体中的 Nanonewton机械稳定性的机制

Rafael C Bernardi1, Ellis Durner2, Constantin Schoeler2

  • 1Beckman Institute for Advanced Science and Technology , University of Illinois at Urbana-Champaign , Urbana , Illinois 61801 , United States.

Journal of the American Chemical Society
|August 30, 2019
PubMed
概括

分子动力学模拟与实验相结合,可以准确预测蛋白质的复杂机械行为. 由于其架构,X模块-多克林 (XDoc) 和Cohesin (Coh) 复合体表现出显著的稳定性,X模块保护其免受破裂.

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