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Updated: Jan 20, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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在2-Oxoglutarate依赖氧酶,TauD中的大型氧联重组的结构起源

Christopher W John1, Robert P Hausinger2,3, Denis A Proshlyakov1

  • 1Department of Chemistry , Michigan State University , East Lansing , Michigan 48824 , United States.

Journal of the American Chemical Society
|September 3, 2019
PubMed
概括

与氨酸酸酸酶 (TauD) 等2氧格酸盐 (2OG) 依赖的氧化酶中氧化潜力的调整与酶结构变化有关. 调查活跃部位的变体揭示了影响这种动态过程的关键残留物.

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