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Updated: Jan 20, 2026

DNA Methylation Analysis
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Published on: April 30, 2023

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基因组标记H3K36me2招募DNMT3A并塑造基因间DNA甲基化格局

Daniel N Weinberg1, Simon Papillon-Cavanagh2, Haifen Chen2

  • 1Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA.

Nature
|September 6, 2019
PubMed
概括

基因组甲基转移酶NSD1将DNA甲基转移酶DNMT3A引入基因间区域,保持DNA甲基化. 突变会破坏这种途径,将异常甲基化与发育障碍和癌症联系起来.

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