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相关概念视频

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro10:01

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

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At the interface of organic and aqueous solvents, tailored amphiphilic elastin-like proteins assemble into complex supramolecular structures such as vesicles, fibers and coacervates triggered by environmental parameters. The described assembly protocols yield Protein Membrane-Based Compartments (PMBCs) with tunable properties, enabling the encapsulation of various...
6.3K
Synthesis and Characterization of Supramolecular Colloids09:26

Synthesis and Characterization of Supramolecular Colloids

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A protocol for the synthesis and characterization of colloids coated with supramolecular moieties is described. These supramolecular colloids undergo self-assembly upon the activation of the hydrogen-bonds between the surface-anchored molecules by...
10.4K
A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry04:32

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

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We describe an in-solution method to apply uniform shear to platelet surface receptors using cone-plate viscometry. This method may also be used more broadly to apply shear to other cell types and cell-fragments and need not target a specific ligand-receptor...
8.1K
Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets05:49

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets

1.1K
Procoagulant platelet formation has been correlated with an increased risk of thrombosis. Presented here is a precise protocol for isolating washed platelets from human blood, intended to quantify the exposure of phosphatidylserine and microvesicle release, which are distinctive features of procoagulant...
1.1K
Studying the Supramolecular Organization of Photosynthetic Membranes within Freeze-fractured Leaf Tissues by Cryo-scanning Electron Microscopy13:52

Studying the Supramolecular Organization of Photosynthetic Membranes within Freeze-fractured Leaf Tissues by Cryo-scanning Electron Microscopy

13.2K
Here we describe a procedure for studying freeze-fractured plant tissues. High-pressure frozen leaf samples are freeze-fractured and double-layer coated, yielding well preserved frozen-hydrated samples that are imaged using the cryo-scanning electron microscope at high magnifications with minimal beam...
13.2K
Uniform Distribution01:19

Uniform Distribution

6.0K
The uniform distribution is a continuous probability distribution of events with an equal probability of occurrence. This distribution is rectangular.
Two essential properties of this distribution are
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相关实验视频

Updated: Jan 19, 2026

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
10:01

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Published on: April 8, 2020

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具有统一和精确控制的高分子六角血小板组件

Gangfeng Chen, Guangpu Zhang, Bixin Jin

  • 1RIKEN Centre for Emergent Matter Science , Saitama 351-0198 , Japan.

Journal of the American Chemical Society
|September 12, 2019
PubMed
概括

研究人员开发了一种新方法,使用晶体纳入复合体从柔软材料中制造精确的六角血小板. 这种超分子组装技术允许控制尺寸和形成同心六角结构.

科学领域:

  • 材料科学
  • 超分子化学
  • 纳米技术

背景情况:

  • 几何结构在自然和工程系统中普遍存在.
  • 从下到上制造精确的几何组件,特别是从柔软的材料制造,仍然是一个重大挑战.

研究的目的:

  • 介绍一种制造体稳定的六角血小板的一般方法.
  • 在软材料合成几何组件时实现精确的尺寸控制.

主要方法:

  • 使用tris-o-phenylenedioxycyclotriphosphazene和块共聚物的结晶合体的形成.
  • 在包含复合体内利用螺杆脱位生长以形成血小板.
  • 使用渐进的种子生长来产生同心六角血小板.

主要成果:

  • 成功制备具有可控制尺寸的均六角血小板.
  • 通过种子生长方法表现出产生同心六角血小板的能力.
  • 该方法产生了合稳定的六角组件.

结论:

  • 已经建立了一个通用的有效的超分子组装方法来制造六角形血小板.
  • 精确的尺寸控制可以通过晶体内置复合体的螺丝脱位增长来实现.

更多相关视频

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A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

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相关实验视频

Last Updated: Jan 19, 2026

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
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Synthesis and Characterization of Supramolecular Colloids
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Synthesis and Characterization of Supramolecular Colloids

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A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry
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A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

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  • 这种方法为从柔软材料中创建复杂的几何结构提供了途径.