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Updated: Jan 19, 2026

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紫外线诱导的瘤异质性降低了黑色素瘤的免疫反应

Yochai Wolf1, Osnat Bartok1, Sushant Patkar2

  • 1Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.

Cell
|September 17, 2019
PubMed
概括

瘤异质性 (ITH) 影响了对癌症的免疫反应. 降低ITH可以增强抗瘤免疫力和T细胞活性,改善黑色素瘤患者的存活率和免疫检查点治疗反应.

关键词:
抗瘤免疫力癌症新抗原检查点免疫治疗瘤内异质性黑色素瘤鼠标模型突变负载

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