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序列定义的登龙指令登龙化二烯基的超分子轮组件

Benjamin E Partridge¹, Li Wang^1,2, Dipankar Sahoo¹

¹Roy & Diana Vagelos Laboratories, Department of Chemistry , University of Pennsylvania , Philadelphia , Pennsylvania 19104-6323 , United States.

Journal of the American Chemical Society

|September 19, 2019

概括

序列定义的树突可以更快地自组装烯二氧化物 (PBI) 超分子结构. 这一突破使得高度有序的轮阶段可用,为合成系统提供了新的可能性.

科学领域:

超分子化学
材料科学
有机化学

背景情况:

二氧化物 (PBIs) 可以自组织成有序的超分子结构.
之前报道的一种状PBI形成了双螺旋的六角阵列,并采用了轮组装模型.
实现这个有序的阶段需要缓慢的加热/冷却或回火,而线性PBI没有这种组合.

研究的目的:

调查序列定义的树突如何影响烯二氧化物 (PBIs) 的自组装.
探索线性和血性链组合在PBI自组合中的作用.
加速PBI中高度排序的轮阶段的形成.

主要方法:

一个具有不同链组成的序列定义的树突库的合成.
使用这些块构建自组装PBI.
使用差分扫描热量计 (DSC) 的热量分析.
使用光纤X射线衍射 (XRD) 的结构分析.

主要成果:

纳入n-链显著加快了高阶轮阶段的形成.
在标准的加热和冷却速度下,可以进入轮阶段.
树突序列中的构成性异构 (例如,甲基转移) 导致了宏观性质的显著变化,如化行为.
一个特定的序列被发现,自组织成轮组装比同人体类似物更快.

结论:

序列定义的初级结构在等级PBI组合中决定了三级和四级结构.
定义序列在超分子合成系统中起着至关重要的作用,类似于其在生物大分子中的作用.
这项研究展示了一种通过控制分子序列快速访问高度排序的超分子结构的方法.

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