在Drosophila中白天的颜色偏好取决于昼夜时钟和TRP通道
Stanislav Lazopulo1, Andrey Lazopulo1, James D Baker2
1Department of Physics, University of Miami, Coral Gables, FL, USA.
Nature
|September 20, 2019
概括
果表现出复杂的,取决于时间的颜色偏好,在早上/下午喜欢绿色光,但避免蓝色光. 这种先天性行为涉及特定的光受体,昼夜时钟定时和各种瞬态受体潜能 (TRP) 通道.
科学领域:
- 神经科学
- 动物的行为
- 时间生物学
背景情况:
- 颜色差别提供了生存优势, 引导动物到资源和远离危险.
- 在各种生物体中,先天的颜色偏好是确立的,但哺乳动物和更简单的物种的数据是有限的,有时也是有争议的.
研究的目的:
- 研究果 (Drosophila) 的天生的色彩偏好模式.
- 识别依赖时间的颜色选择的分子和神经机制.
- 探索生理时钟在调节视觉行为的作用.
主要方法:
- 让果在蓝光,绿光和暗光之间做出选择.
- 研究特定光受体和瞬态受体潜能 (TRP) 通道的基因操纵.
- 对生理时钟对颜色偏好的影响进行分析.
主要成果:
- 果在早晨和下午晚些时候更喜欢绿色光线,
- 一整天都避免使用蓝光.
- 绿色光的偏好由罗多素光受体介导,并由昼夜时钟调节.
- 中午偏好暗光涉及TRP通道dTRPA1和Pyrexia,也在昼夜控制下.
- 避开蓝光依赖于多核神经元,素7和TRP通道 无痛,独立于时钟.
结论:
- 草的天生的色彩偏好是复杂的,并由一天中的时间动态调节.
- 不同的神经通路涉及不同的光受体和TRP通道调解对不同颜色的反应.
- 生物钟在协调这些由颜色驱动的行为中起着至关重要的作用,
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