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Updated: Jan 15, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
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在酶合作性中的低障碍键

Shaobo Dai1,2, Lisa-Marie Funk1,2, Fabian Rabe von Pappenheim1,2

  • 1Department of Molecular Enzymology, Göttingen Centre for Molecular Biosciences and Albrecht-von-Haller Institute, Georg-August University Göttingen, Göttingen, Germany.

Nature
|September 20, 2019
PubMed
概括

研究人员发现波动的低屏障键作为酶合作的分子开关. 这种机制解释了远程信号传递,并为蛋白质和药物设计提供了新的途径.

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