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Updated: Jan 6, 2026

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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人类Rag GTPase异构体及其与mTORC1复合物的结构

Madhanagopal Anandapadamanaban1, Glenn R Masson1, Olga Perisic1

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Science (New York, N.Y.)
|October 12, 2019
PubMed
概括

拉格GTPase与mTORC1结合,调节基于氨基酸的细胞生长. 它们的核酸状态控制了这种结合,RagAGTP/RagCGDP等特定状态对于mTORC1的招募和激活至关重要.

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