用管状核酸编码碳纳米管用于信息存储
Yueyue Zhang1,2, Fan Li1, Min Li1
1Institute of Molecular Medicine, State Key Laboratory of Oncogenes and Related Genes, Renji Hospital, School of Medicine and School of Chemistry and Chemical Engineering , Shanghai Jiao Tong University , Shanghai 200127 , China.
Journal of the American Chemical Society
|October 12, 2019
概括
研究人员在碳纳米管 (CNT) 上制造了管状核酸 (TNA) 用于数据存储. 这种基于DNA的方法使用特定序列的相互作用和独特的模式来编码视觉信息,而无需混合.
科学领域:
- 纳米技术
- 生物材料科学
- 信息存储
背景情况:
- 脱氧核酸 (DNA) 对于遗传信息的存储和传输至关重要.
- 目前的体外DNA数据存储方法通常依赖于DNA杂交反应.
- 需要新的非混合基的DNA数据存储策略.
研究的目的:
- 通过在碳纳米管 (CNT) 上凝结DNA,开发一种新型的管状核酸 (TNA).
- 研究DNA和CNT之间的特定序列相互作用.
- 展示TNA-CNT复合物的信息存储潜力.
主要方法:
- 在一维碳纳米管 (CNT) 的表面上凝结DNA链.
- 原子力显微镜 (AFM) 用于成像TNA结构和图案.
- 对DNA-CNT相互作用和由此产生的形状 (螺旋,i-motif,G-quadruplex) 的表征.
主要成果:
- DNA以特定序列的方式与 CNT 相互作用,形成不同的形状.
- CNT上的TNA具有可测量的高度和距离特征的独特模式.
- 成功展示了用于视觉信息存储的TNA-CNT.
结论:
- 开发的TNA-CNT系统为基于DNA的数据存储提供了一种新方法.
- 序列特定的DNA-CNT相互作用和由此产生的模式使二维编码成为可能.
- 这种无混合的策略扩大了先进信息存储材料的可能性.
相关概念视频
Nucleic Acid Structure
8.3K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
DNA Structure
DNA...
8.3K
Nucleic acids
188.0K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
188.0K
Nucleic Acids
49.4K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
49.4K
Nucleic Acids
8.7K
8.7K
Nucleic Acids and Nucleotides
13.7K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria....
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria....
13.7K
Genomic DNA in Eukaryotes
52.0K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
52.0K


