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Microbial Growth Measurement: Indirect Methods

Microbial Growth Measurement: Indirect Methods

Estimating microbial growth is essential for understanding population dynamics and environmental adaptations. Indirect methods provide valuable insights by measuring parameters such as turbidity, metabolic activity, and biomass, enabling efficient and reproducible assessments.During exponential growth, microbial cells scatter light proportionally to their biomass, a principle used in turbidity measurements. About one million cells per milliliter produce detectable scattering, which a...

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Micro-masonry for 3D Additive Micromanufacturing

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Published on: August 1, 2014

可扩展的亚微米增材制造

Sourabh K Saha¹, Dien Wang², Vu H Nguyen³

¹Center for Engineered Materials and Manufacturing, Lawrence Livermore National Laboratory, Livermore, CA, USA. sourabh.saha@me.gatech.edu scchen@mae.cuhk.edu.hk.

Science (New York, N.Y.)

|October 12, 2019

概括

研究人员开发了一种使用聚焦激光进行纳米制造的快速3D打印方法. 这种先进的双光子光刻 (TPL) 技术显著提高了复杂微观结构的生产速度.

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科学领域:

材料科学
纳米技术
添加剂制造

背景情况:

具有纳米尺度特征的复杂3D结构的高通量制造对于各种应用至关重要.
双光子光刻 (TPL) 提供亚微米分辨率,但受到缓慢的连续写作速度的影响.
现有的TPL平行化方法缺乏微米分辨率或结构复杂性.

研究的目的:

为制造复杂的3D纳米结构开发高通量并行TPL技术.
在保持纳米分辨率的同时克服传统TPL的速度限制.
扩大复杂设计的增材制造能力.

主要方法:

使用空间和时间聚焦的超快激光实现了基于投影的层次平行化策略.
使用先进的光学技术,
在毫秒时间尺度上演示了制造过程.

主要成果:

与传统的TPL相比,实现了高达三倍的吞吐量增加.
成功打印了宽度低于175纳米的纳米线.
在一个比激光截面面积大一百万倍的区域上展示了平行制造.

结论:

这种基于投影的新型平行化显著提高了TPL吞吐量,并扩大了设计可能性.
这种方法可以快速,高分辨率的复杂3D纳米结构的增材制造.
这种技术有可能在需要纳米制造的领域加速发展.