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相关概念视频

Separation of Sister Chromatids02:17

Separation of Sister Chromatids

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At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...
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The Spindle Assembly Checkpoint02:19

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The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...
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相关实验视频

Updated: Jan 5, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
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Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

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快照:S阶段进入和退出

Andrew Burgess1, Jenny Vuong2, Kamila A Marzec1

  • 1ANZAC Research Institute, University of Sydney, Sydney NSW 2139, Australia.

Cell
|October 19, 2019
PubMed
概括
此摘要是机器生成的。

这项研究可视化了80多个调节细胞周期S阶段进入和退出的关键事件. 新的S阶段可视化补充了现有的M阶段可视化,提供了完整的细胞分裂概述.

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Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae
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Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae

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Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
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Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

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相关实验视频

Last Updated: Jan 5, 2026

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Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

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Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae
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Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae

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Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
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科学领域:

  • 细胞生物学
  • 分子生物学
  • 生物化学

背景情况:

  • 细胞循环的进展依赖于蛋白质复合组合的精确时间.
  • 了解S阶段 (合成阶段) 的调节对于细胞分裂至关重要.

研究的目的:

  • 创建一个全面的S相调节可视化.
  • 将S阶段事件与现有的M阶段可视化集成为整体细胞周期视图.

主要方法:

  • 使用Minardo布局开发了一个定制的可视化.
  • 突出了80多个重要的S阶段调控事件.

主要成果:

  • 一个详细的S阶段进入和退出调节可见现在.
  • S阶段可视化补充了之前开发的M阶段可视化.

结论:

  • 组合可视化提供了细胞分裂周期调节的全面概述.
  • 这种资源有助于了解细胞分裂的相互作用.